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TNF-α Stimulates Colonic Myofibroblast Migration via COX-2 and Hsp27

BACKROUND: Crohn’s disease (CD) is a chronic inflammatory enteropathy characterized by fibrotic strictures. Myofibroblasts (MFB) are stromal cells of the GI tract found in increased numbers in patients with CD and represent the key effector cells involved in pathologic fibrosis. MFB are a known targ...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Saini, Shyla, Liu, Tiegang, Yoo, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391874/
https://ncbi.nlm.nih.gov/pubmed/27451881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2016.04.034
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