Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17

We previously showed that the cell adhesion molecule Nectin-4 is overexpressed in ovarian cancer tumors, and its cleaved extracellular domain can be detected in the serum of ovarian cancer patients. The ADAM (a disintegrin and metalloproteinase) proteases are involved in ectodomain cleavage of trans...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Buchanan, Petra C., Boylan, Kristin L. M., Walcheck, Bruce, Heinze, Rachel, Geller, Melissa A., Argenta, Peter A., Skubitz, Amy P. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391762/
https://ncbi.nlm.nih.gov/pubmed/28232483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.746859
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados