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Genetic and Environmental Factors Influencing Glutathione Homeostasis in Saccharomyces cerevisiae

Glutathione is an essential metabolite protecting cells against oxidative stress and aging. Here, we show that endogenously synthesized glutathione undergoes intercellular cycling during growth to stationary phase. Genome-wide screening identified ∼270 yeast deletion mutants that overexcrete glutath...

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Bibliografiske detaljer
Main Authors: Perrone, Gabriel G., Grant, Chris M., Dawes, Ian W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC539166/
https://ncbi.nlm.nih.gov/pubmed/15509654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-07-0560
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