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Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for Epithelial Integrity
The Rap-pathway has been implicated in various cellular processes but its exact physiological function remains poorly defined. Here we show that the Caenorhabditis elegans homologue of the mammalian guanine nucleotide exchange factors PDZ-GEFs, PXF-1, specifically activates Rap1 and Rap2. Green fluo...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539156/ https://ncbi.nlm.nih.gov/pubmed/15525675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-06-0492 |
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