A single non-synonymous NCOA5 variation in type 2 diabetic patients with hepatocellular carcinoma impairs the function of NCOA5 in cell cycle regulation

Type 2 Diabetes (T2D) is a risk factor for hepatocellular carcinoma (HCC). We have previously described that haploinsufficiency of nuclear receptor coactivator 5 (NCOA5) is a genetic defect linking glucose intolerance to HCC. Here we report identification and characterization of a single nucleotide...

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Publicado no:Cancer Lett
Main Authors: Liu, Xinhui, Liu, Feiye, Gao, Shenglan, Reske, Jake, Li, Aimin, Wu, Chin-Lee, Yang, Chengfeng, Chen, Fengsheng, Luo, Rongcheng, Xiao, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391530/
https://ncbi.nlm.nih.gov/pubmed/28137631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.01.028
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