Protein kinase D2 contributes to TNF-α-induced epithelial mesenchymal transition and invasion via the PI3K/GSK-3β/β-catenin pathway in hepatocellular carcinoma

Although protein kinase D (PKD) has been shown to contribute to invasion and metastasis in several types of cancer, the role of PKD in the epithelial mesenchymal transition (EMT) of hepatocellular carcinoma (HCC) has remained unclear. We found that PKD2 is up-regulated in HCC and is correlated with...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhu, Yun, Cheng, Yang, Guo, YaBin, Chen, JinZhang, Chen, FengSheng, Luo, RongCheng, Li, AiMin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868689/
https://ncbi.nlm.nih.gov/pubmed/26683365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6633
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