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TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice

Lung adenocarcinoma, the most common type of human non-small cell lung cancer (NSCLC), frequently overexpresses EGFR. However, the mechanisms underlying EGFR overexpression are not completely understood. Recent studies have identified that decreased expression of TIP30 is associated with the metasta...

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Bibliographic Details
Main Authors: Li, Aimin, Zhang, Chengliang, Gao, Shenglan, Chen, Fengsheng, Yang, Chengfen, Luo, Rongcheng, Xiao, Hua
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460142/
https://ncbi.nlm.nih.gov/pubmed/22733137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.253
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