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Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products
[Image: see text] A thermodynamic approach to peptide macrocyclization inspired by the cyclization of non-ribosomal peptide aldehydes is presented. The method provides access to structurally diverse macrocycles by exploiting the reactivity of transient macrocyclic peptide imines toward inter- and in...
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Publicado no: | J Am Chem Soc |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2017
|
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391502/ https://ncbi.nlm.nih.gov/pubmed/28326777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01624 |
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