The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR). The UPR is relayed to the cell through the activation of PERK, IRE1/XBP1, and ATF6. Here, we demonstr...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Xiong, Guangyan, Hindi, Sajedah M, Mann, Aman K, Gallot, Yann S, Bohnert, Kyle R, Cavener, Douglas R, Whittemore, Scott R, Kumar, Ashok
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391206/
https://ncbi.nlm.nih.gov/pubmed/28332979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22871
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