The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR). The UPR is relayed to the cell through the activation of PERK, IRE1/XBP1, and ATF6. Here, we demonstr...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Xiong, Guangyan, Hindi, Sajedah M, Mann, Aman K, Gallot, Yann S, Bohnert, Kyle R, Cavener, Douglas R, Whittemore, Scott R, Kumar, Ashok
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2017
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391206/
https://ncbi.nlm.nih.gov/pubmed/28332979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22871
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