The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR). The UPR is relayed to the cell through the activation of PERK, IRE1/XBP1, and ATF6. Here, we demonstr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Xiong, Guangyan, Hindi, Sajedah M, Mann, Aman K, Gallot, Yann S, Bohnert, Kyle R, Cavener, Douglas R, Whittemore, Scott R, Kumar, Ashok
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391206/
https://ncbi.nlm.nih.gov/pubmed/28332979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22871
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