From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints

Elementary flux modes (EFMs) emerged as a formal concept to describe metabolic pathways and have become an established tool for constraint-based modeling and metabolic network analysis. EFMs are characteristic (support-minimal) vectors of the flux cone that contains all feasible steady-state flux ve...

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Bibliografiska uppgifter
I publikationen:PLoS Comput Biol
Huvudupphovsmän: Klamt, Steffen, Regensburger, Georg, Gerstl, Matthias P., Jungreuthmayer, Christian, Schuster, Stefan, Mahadevan, Radhakrishnan, Zanghellini, Jürgen, Müller, Stefan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390976/
https://ncbi.nlm.nih.gov/pubmed/28406903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005409
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