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A mathematical framework for yield (vs. rate) optimization in constraint-based modeling and applications in metabolic engineering
Background: The optimization of metabolic rates (as linear objective functions) represents the methodical core of flux-balance analysis techniques which have become a standard tool for the study of genome-scale metabolic models. Besides (growth and synthesis) rates, metabolic yields are key paramete...
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| Veröffentlicht in: | Metab Eng |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Academic Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992331/ https://ncbi.nlm.nih.gov/pubmed/29427605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2018.02.001 |
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