Metformin inhibited esophageal squamous cell carcinoma proliferation in vitro and in vivo and enhanced the anti-cancer effect of cisplatin

Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with poor prognosis in China. Chemotherapy now is one of the most frequently used treatments for patients with ESCC in middle or late stage, however the effects were often limited by increased chemoresistance or treatment toxicity...

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Udgivet i:PLoS One
Main Authors: Wang, Feng, Ding, Xianfei, Wang, Tao, Shan, Zhengzheng, Wang, Jun, Wu, Shaoxuan, Chi, Yanyan, Zhang, Yana, Lv, Zhuan, Wang, Liuxing, Fan, Qingxia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390971/
https://ncbi.nlm.nih.gov/pubmed/28406985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174276
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