Metformin inhibited esophageal squamous cell carcinoma proliferation in vitro and in vivo and enhanced the anti-cancer effect of cisplatin

Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with poor prognosis in China. Chemotherapy now is one of the most frequently used treatments for patients with ESCC in middle or late stage, however the effects were often limited by increased chemoresistance or treatment toxicity...

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Publicado en:PLoS One
Autores principales: Wang, Feng, Ding, Xianfei, Wang, Tao, Shan, Zhengzheng, Wang, Jun, Wu, Shaoxuan, Chi, Yanyan, Zhang, Yana, Lv, Zhuan, Wang, Liuxing, Fan, Qingxia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390971/
https://ncbi.nlm.nih.gov/pubmed/28406985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174276
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