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Mitochondria-associated ER membranes and Alzheimer Disease

The series of events underlying the pathogenesis of Alzheimer disease (AD) in unknown. The most widely-accepted hypothesis is called the amyloid cascade, based on the observation that the brains of AD patients contain high levels of extracellular plaques, composed mainly of β-amyloid (Aβ), and intra...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Area-Gomez, Estela, Schon, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390896/
https://ncbi.nlm.nih.gov/pubmed/27235807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2016.04.006
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