Bicarbonate sensing in mouse cortical astrocytes during extracellular acid/base disturbances

KEY POINTS: The present study suggests that the electrogenic sodium–bicarbonate cotransporter, NBCe1, supported by carbonic anhydrase II, CAII, provides an efficient mechanism of bicarbonate sensing in cortical astrocytes. This mechanism is proposed to play a major role in setting the pH(i) response...

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Veröffentlicht in:J Physiol
Hauptverfasser: Theparambil, Shefeeq M., Naoshin, Zinnia, Defren, Sabrina, Schmaelzle, Jana, Weber, Tobias, Schneider, Hans‐Peter, Deitmer, Joachim W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Neuroscience ‐ cellular/molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390880/
https://ncbi.nlm.nih.gov/pubmed/27981578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273394
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