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Bicarbonate sensing in mouse cortical astrocytes during extracellular acid/base disturbances

KEY POINTS: The present study suggests that the electrogenic sodium–bicarbonate cotransporter, NBCe1, supported by carbonic anhydrase II, CAII, provides an efficient mechanism of bicarbonate sensing in cortical astrocytes. This mechanism is proposed to play a major role in setting the pH(i) response...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Theparambil, Shefeeq M., Naoshin, Zinnia, Defren, Sabrina, Schmaelzle, Jana, Weber, Tobias, Schneider, Hans‐Peter, Deitmer, Joachim W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390880/
https://ncbi.nlm.nih.gov/pubmed/27981578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273394
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