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Bicarbonate sensing in mouse cortical astrocytes during extracellular acid/base disturbances

KEY POINTS: The present study suggests that the electrogenic sodium–bicarbonate cotransporter, NBCe1, supported by carbonic anhydrase II, CAII, provides an efficient mechanism of bicarbonate sensing in cortical astrocytes. This mechanism is proposed to play a major role in setting the pH(i) response...

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Pubblicato in:J Physiol
Autori principali: Theparambil, Shefeeq M., Naoshin, Zinnia, Defren, Sabrina, Schmaelzle, Jana, Weber, Tobias, Schneider, Hans‐Peter, Deitmer, Joachim W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390880/
https://ncbi.nlm.nih.gov/pubmed/27981578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273394
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