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Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes

Recovery of intracellular pH from cytosolic alkalosis has been attributed primarily to Cl(–) coupled acid loaders/base extruders such as Cl(–)/HCO(3)(–) or Cl(–)/OH(–) exchangers. We have studied this process in cortical astrocytes from wild-type and transgenic mouse models with gene deletion for th...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Theparambil, Shefeeq M, Naoshin, Zinnia, Thyssen, Anne, Deitmer, Joachim W
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560583/
https://ncbi.nlm.nih.gov/pubmed/25990710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270086
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