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Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study

BACKGROUND: The phase III COntinuous or INtermittent (COIN) trial failed to demonstrate a benefit in overall survival of cetuximab in combination with chemotherapy for patients with metastatic colorectal cancer (mCRC). High derived neutrophil to lymphocyte ratio (dNLR) has been shown to be prognosti...

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Publicat a:Anticancer Drugs
Autors principals: Wood, Georgina, Grenader, Tal, Nash, Stephen, Adams, Richard, Kaplan, Richard, Fisher, David, Maughan, Tim, Bridgewater, John
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390854/
https://ncbi.nlm.nih.gov/pubmed/28252533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000488
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