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Tetrahydropyranyl: A Non‐aromatic, Mild‐Acid‐Labile Group for Hydroxyl Protection in Solid‐Phase Peptide Synthesis
The use of the tetrahydropyranyl (Thp) group for the protection of serine and threonine side‐chain hydroxyl groups in solid‐phase peptide synthesis has not been widely investigated. Ser/Thr side‐chain hydroxyl protection with this acid‐labile and non‐aromatic moiety is presented here. Although Thp r...
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| Publicado en: | ChemistryOpen |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390794/ https://ncbi.nlm.nih.gov/pubmed/28413752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600157 |
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