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Structural Basis for the 14-3-3 Protein-Dependent Inhibition of Phosducin Function
Phosducin (Pdc) is a conserved phosphoprotein that, when unphosphorylated, binds with high affinity to the complex of βγ-subunits of G protein transducin (G(t)βγ). The ability of Pdc to bind to G(t)βγ is inhibited through its phosphorylation at S54 and S73 within the N-terminal domain (Pdc-ND) follo...
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| Publié dans: | Biophys J |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390052/ https://ncbi.nlm.nih.gov/pubmed/28402877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.036 |
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