Competitive binding between Seryl-tRNA synthetase/YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis

Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis. Previous studies focused on transcriptional regulation modulated by proximal upstream cis-regulatory elements (CREs) of the human vegfa promoter. However, we hypothesized that distal upstream CREs may also be involved in...

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Udgivet i:Nucleic Acids Res
Main Authors: Fu, Chuan-Yang, Wang, Po-Chun, Tsai, Huai-Jen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389716/
https://ncbi.nlm.nih.gov/pubmed/27913726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1187
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