Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity

The androgen receptor (AR) is the main driver of prostate cancer (PC) development and progression, and the primary therapeutic target in PC. To date, two functional ubiquitination sites have been identified on AR, both located in its C-terminal ligand binding domain (LBD). Recent reports highlight t...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: McClurg, Urszula L., Cork, David M.W., Darby, Steven, Ryan-Munden, Claudia A., Nakjang, Sirintra, Mendes Côrtes, Leticia, Treumann, Achim, Gaughan, Luke, Robson, Craig N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Gene regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389688/
https://ncbi.nlm.nih.gov/pubmed/27903893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1162
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