Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis

Histone demethylase PHF8 is upregulated and plays oncogenic roles in various cancers; however, the mechanisms underlying its dysregulation and functions in carcinogenesis remain obscure. Here, we report the novel functions of PHF8 in EMT (epithelial to mesenchymal transition) and breast cancer devel...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Shao, Peng, Liu, Qi, Maina, Peterson Kariuki, Cui, Jiayue, Bair, Thomas B., Li, Tiandao, Umesalma, Shaikamjad, Zhang, Weizhou, Qi, Hank Heng
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Gene regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389682/
https://ncbi.nlm.nih.gov/pubmed/27899639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1093
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