Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis

Histone demethylase PHF8 is upregulated and plays oncogenic roles in various cancers; however, the mechanisms underlying its dysregulation and functions in carcinogenesis remain obscure. Here, we report the novel functions of PHF8 in EMT (epithelial to mesenchymal transition) and breast cancer devel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Shao, Peng, Liu, Qi, Maina, Peterson Kariuki, Cui, Jiayue, Bair, Thomas B., Li, Tiandao, Umesalma, Shaikamjad, Zhang, Weizhou, Qi, Hank Heng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Gene regulation, Chromatin and Epigenetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389682/
https://ncbi.nlm.nih.gov/pubmed/27899639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1093
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