Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding

Expression of bacterial type II toxin-antitoxin (TA) systems is regulated at the transcriptional level through direct binding of the antitoxin to pseudo-palindromic sequences on operator DNA. In this context, the toxin functions as a co-repressor by stimulating DNA binding through direct interaction...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Bendtsen, Kirstine L., Xu, Kehan, Luckmann, Majbritt, Winther, Kristoffer S., Shah, Shiraz A., Pedersen, Christian N. S., Brodersen, Ditlev E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389673/
https://ncbi.nlm.nih.gov/pubmed/27998932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1266
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