Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli

Yield of protein per translated mRNA may vary by four orders of magnitude. Many studies analyzed the influence of mRNA features on the translation yield. However, a detailed understanding of how mRNA sequence determines its propensity to be translated is still missing. Here, we constructed a set of...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Evfratov, Sergey A., Osterman, Ilya A., Komarova, Ekaterina S., Pogorelskaya, Alexandra M., Rubtsova, Maria P., Zatsepin, Timofei S., Semashko, Tatiana A., Kostryukova, Elena S., Mironov, Andrey A., Burnaev, Evgeny, Krymova, Ekaterina, Gelfand, Mikhail S., Govorun, Vadim M., Bogdanov, Alexey A., Sergiev, Petr V., Dontsova, Olga A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389652/
https://ncbi.nlm.nih.gov/pubmed/27899632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1141
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