Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli

Yield of protein per translated mRNA may vary by four orders of magnitude. Many studies analyzed the influence of mRNA features on the translation yield. However, a detailed understanding of how mRNA sequence determines its propensity to be translated is still missing. Here, we constructed a set of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Evfratov, Sergey A., Osterman, Ilya A., Komarova, Ekaterina S., Pogorelskaya, Alexandra M., Rubtsova, Maria P., Zatsepin, Timofei S., Semashko, Tatiana A., Kostryukova, Elena S., Mironov, Andrey A., Burnaev, Evgeny, Krymova, Ekaterina, Gelfand, Mikhail S., Govorun, Vadim M., Bogdanov, Alexey A., Sergiev, Petr V., Dontsova, Olga A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389652/
https://ncbi.nlm.nih.gov/pubmed/27899632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1141
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