Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli

Yield of protein per translated mRNA may vary by four orders of magnitude. Many studies analyzed the influence of mRNA features on the translation yield. However, a detailed understanding of how mRNA sequence determines its propensity to be translated is still missing. Here, we constructed a set of...

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Publicado en:Nucleic Acids Res
Autores principales: Evfratov, Sergey A., Osterman, Ilya A., Komarova, Ekaterina S., Pogorelskaya, Alexandra M., Rubtsova, Maria P., Zatsepin, Timofei S., Semashko, Tatiana A., Kostryukova, Elena S., Mironov, Andrey A., Burnaev, Evgeny, Krymova, Ekaterina, Gelfand, Mikhail S., Govorun, Vadim M., Bogdanov, Alexey A., Sergiev, Petr V., Dontsova, Olga A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389652/
https://ncbi.nlm.nih.gov/pubmed/27899632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1141
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