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MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma
The oncogenic transcription factor MYC and its binding partner MAX regulate gene expression by binding to DNA at enhancer-box (E-box) elements 5΄-CACGTG-3΄. In mammalian genomes, the central E-box CpG has the potential to be methylated at the 5-position of cytosine (5mC), or to undergo further oxida...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389568/ https://ncbi.nlm.nih.gov/pubmed/27903915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1184 |
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