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Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks
The DNA replication or S-phase checkpoint monitors the integrity of DNA synthesis. Replication stress or DNA damage triggers fork stalling and checkpoint signaling to activate repair pathways. Recovery from checkpoint activation is critical for cell survival following DNA damage. Recovery from the S...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389566/ https://ncbi.nlm.nih.gov/pubmed/27956499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1249 |
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