A carregar...
A novel role for GSK3β as a modulator of Drosha microprocessor activity and MicroRNA biogenesis
Regulation of microRNA (miR) biogenesis is complex and stringently controlled. Here, we identify the kinase GSK3β as an important modulator of miR biogenesis at Microprocessor level. Repression of GSK3β activity reduces Drosha activity toward pri-miRs, leading to accumulation of unprocessed pri-miRs...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389555/ https://ncbi.nlm.nih.gov/pubmed/27907888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw938 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|