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Nucleolin Protein Interacts with Microprocessor Complex to Affect Biogenesis of MicroRNAs 15a and 16

MicroRNAs (miRNA) are endogenous, short, non-coding RNA that undergo a multistep biogenesis before generating the functional, mature sequence. The core components of the microprocessor complex, consisting of Drosha and DGCR8, are both necessary and sufficient for this process, although accessory pro...

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Detalhes bibliográficos
Main Authors: Pickering, Brian F., Yu, Dihua, Van Dyke, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243533/
https://ncbi.nlm.nih.gov/pubmed/22049078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.265439
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