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A structure–function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance
The sliding clamp, PCNA, plays a central role in DNA replication and repair. In the moving replication fork, PCNA is present at the leading strand and at each of the Okazaki fragments that are formed on the lagging strand. PCNA enhances the processivity of the replicative polymerases and provides a...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389545/ https://ncbi.nlm.nih.gov/pubmed/28108661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1348 |
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