A Genetic Screen for High Copy Number Suppressors of the Synthetic Lethality Between elg1Δ and srs2Δ in Yeast

Elg1 and Srs2 are two proteins involved in maintaining genome stability in yeast. After DNA damage, the homotrimeric clamp PCNA, which provides stability and processivity to DNA polymerases and serves as a docking platform for DNA repair enzymes, undergoes modification by the ubiquitin-like molecule...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gazy, Inbal, Liefshitz, Batia, Bronstein, Alex, Parnas, Oren, Atias, Nir, Sharan, Roded, Kupiec, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Genetics Society of America 2013
Gaiak:
Mutant Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656737/
https://ncbi.nlm.nih.gov/pubmed/23704284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.005561
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