Biophysical properties, thermal stability and functional impact of 8-oxo-7,8-dihydroguanine on oligonucleotides of RNA—a study of duplex, hairpins and the aptamer for preQ(1) as models

A better understanding of the effects that oxidative lesions have on RNA is of importance to understand their role in the development/progression of disease. 8-oxo-7,8-dihydroguanine was incorporated into RNA to understand its structural and functional impact on RNA:RNA and RNA:DNA duplexes, hairpin...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Choi, Yu J., Gibala, Krzysztof S., Ayele, Tewoderos, Deventer, Katherine V., Resendiz, Marino J. E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389535/
https://ncbi.nlm.nih.gov/pubmed/28426093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw885
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