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Biophysical Properties and Thermal Stability of Oligonucleotides of RNA Containing 7,8-Dihydro-8-hydroxyadenosine

Circular dichroism (CD) was used to assess the stabilization/destabilization imposed by oxidative lesion 7,8-dihydro-8-hydroxyadenosine (8-oxoA) on strands of RNA with different structural motifs. RNA:RNA homoduplex destabilization was observed in a position dependent manner using 10-mers as models...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Chauca-Diaz, Ana M, Jung Choi, Yu, Resendiz, Marino J E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302245/
https://ncbi.nlm.nih.gov/pubmed/25363418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22579
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