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Discovery and validation of information theory-based transcription factor and cofactor binding site motifs

Data from ChIP-seq experiments can derive the genome-wide binding specificities of transcription factors (TFs) and other regulatory proteins. We analyzed 765 ENCODE ChIP-seq peak datasets of 207 human TFs with a novel motif discovery pipeline based on recursive, thresholded entropy minimization. Thi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lu, Ruipeng, Mucaki, Eliseos J., Rogan, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389469/
https://ncbi.nlm.nih.gov/pubmed/27899659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1036
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