Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient.
GM2 ganglioside is a common cell surface constituent of human melanoma and other tumors of neuroectodermal origin, and vaccination with GM2 ganglioside results in high levels of anti-GM2 antibodies in patients with melanoma. Lymphocytes from a GM2-vaccinated patient (VS) were transformed by Epstein-...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1990
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53894/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3333 |
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