Specificity analysis of human monoclonal antibodies reactive with cell surface and intracellular antigens.

Over 4350 human Ig-secreting hybrids have been generated through the fusion of human lymphocytes with NS-1 (mouse), LICR-2, SKO-007, GM4672, or UC729-6 (human) myeloma and lymphoblastoid cell lines. NS-1 proved to be the most satisfactory fusion partner, and 83% of the stable Ig-secreting clones wer...

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Autors principals: Cote, R J, Morrissey, D M, Houghton, A N, Thomson, T M, Daly, M E, Oettgen, H F, Old, L J
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC323426/
https://ncbi.nlm.nih.gov/pubmed/3458255
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