Specificity analysis of human monoclonal antibodies reactive with cell surface and intracellular antigens.

Over 4350 human Ig-secreting hybrids have been generated through the fusion of human lymphocytes with NS-1 (mouse), LICR-2, SKO-007, GM4672, or UC729-6 (human) myeloma and lymphoblastoid cell lines. NS-1 proved to be the most satisfactory fusion partner, and 83% of the stable Ig-secreting clones wer...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Cote, R J, Morrissey, D M, Houghton, A N, Thomson, T M, Daly, M E, Oettgen, H F, Old, L J
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1986
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323426/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458255/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.9.2959
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