Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient.

GM2 ganglioside is a common cell surface constituent of human melanoma and other tumors of neuroectodermal origin, and vaccination with GM2 ganglioside results in high levels of anti-GM2 antibodies in patients with melanoma. Lymphocytes from a GM2-vaccinated patient (VS) were transformed by Epstein-...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Yamaguchi, H, Furukawa, K, Fortunato, S R, Livingston, P O, Lloyd, K O, Oettgen, H F, Old, L J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53894/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3333
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