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Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis
We established a mouse model of developmental nonalcoholic steatohepatitis (NASH) by feeding a high polyunsaturated fat liquid diet to female glutathione-S-transferase 4-4 (Gsta4(−/−))/peroxisome proliferator activated receptor α (Ppara(−/−)) double knockout 129/SvJ mice for 12 weeks from weaning. W...
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| Publicado no: | Am J Pathol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389362/ https://ncbi.nlm.nih.gov/pubmed/27998724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.10.022 |
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