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Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA

The alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively referred to as (p)ppGpp, are key regulators of bacterial growth, stress adaptation, pathogenicity, and antibiotic tolerance. We show that the tetrameric small alarmone synthetase (SAS) RelQ from the G...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Beljantseva, Jelena, Kudrin, Pavel, Andresen, Liis, Shingler, Victoria, Atkinson, Gemma C., Tenson, Tanel, Hauryliuk, Vasili
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389274/
https://ncbi.nlm.nih.gov/pubmed/28320944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617868114
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