Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA

The alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively referred to as (p)ppGpp, are key regulators of bacterial growth, stress adaptation, pathogenicity, and antibiotic tolerance. We show that the tetrameric small alarmone synthetase (SAS) RelQ from the G...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Beljantseva, Jelena, Kudrin, Pavel, Andresen, Liis, Shingler, Victoria, Atkinson, Gemma C., Tenson, Tanel, Hauryliuk, Vasili
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389274/
https://ncbi.nlm.nih.gov/pubmed/28320944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617868114
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