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Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA.

Cancer treatment with the drug cisplatin is often thwarted by the emergence of drug-resistant cells. To study this phenomenon, we identified two independent cellular factors that recognize cisplatin-damaged DNA. One of the two factors, designated XPE binding factor, is deficient in complementation g...

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Autori principali: Chu, G, Chang, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC53892/
https://ncbi.nlm.nih.gov/pubmed/2333286
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