Characterization of pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis in Brazil

In this study the nucleotide sequence of the pncA gene from 59 Mycobacterium tuberculosis clinical isolates was analyzed. Mutations in the pncA gene were identified in 29 of 40 pyrazinamide-resistant isolates, and no pyrazinamidase activity was detected in 39 of them. Twelve mutations found in this...

Descripción completa

Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Rodrigues, Vívian de F. Sumnienski, Telles, Maria Alice, Ribeiro, Marta Osório, Cafrune, Patrícia Izquierdo, Rossetti, Maria Lucia Rosa, Zaha, Arnaldo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2005
Materias:	Mechanisms of Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616332/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.444-446.2005
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!