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The effects of reduced rpd3 levels on fly physiology

BACKGROUND: Rpd3 is a conserved histone deacetylase that removes acetyl groups from lysine residues within histones and other proteins. Reduction or inhibition of Rpd3 extends longevity in yeast, worms, and flies. Previous studies in flies suggest an overlap with the mechanism of lifespan extension...

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Dades bibliogràfiques
Publicat a:Nutr Healthy Aging
Autors principals: Woods, Jared K., Ziafazeli, Tahereh, Rogina, Blanka
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389049/
https://ncbi.nlm.nih.gov/pubmed/28447071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/NHA-160016
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