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The effects of reduced rpd3 levels on fly physiology

BACKGROUND: Rpd3 is a conserved histone deacetylase that removes acetyl groups from lysine residues within histones and other proteins. Reduction or inhibition of Rpd3 extends longevity in yeast, worms, and flies. Previous studies in flies suggest an overlap with the mechanism of lifespan extension...

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Detalhes bibliográficos
Publicado no:Nutr Healthy Aging
Main Authors: Woods, Jared K., Ziafazeli, Tahereh, Rogina, Blanka
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389049/
https://ncbi.nlm.nih.gov/pubmed/28447071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/NHA-160016
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