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RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity

Single-gene mutations that extend longevity have revealed regulatory pathways related to aging and longevity. RPD3 is a conserved histone deacetylase (Class I HDAC). Previously we showed that Drosophila rpd3 mutations increase longevity. Here we tested the longevity effects of RPD3 on multiple nutri...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Main Authors: Frankel, Stewart, Woods, Jared, Ziafazeli, Tahereh, Rogina, Blanka
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712336/
https://ncbi.nlm.nih.gov/pubmed/26647291
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