Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice

Apart from its potent antioxidant property, recent studies have revealed that melatonin promotes PI3K/Akt phosphorylation following focal cerebral ischemia (FCI) in mice. However, it is not clear (i) whether increased PI3K/Akt phosphorylation is a concomitant event or it directly contributes to mela...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Redox Biol
Hlavní autoři: Kilic, Ulkan, Caglayan, Ahmet Burak, Beker, Mustafa Caglar, Gunal, Mehmet Yalcin, Caglayan, Berrak, Yalcin, Esra, Kelestemur, Taha, Gundogdu, Reyhan Zeynep, Yulug, Burak, Yılmaz, Bayram, Kerman, Bilal Ersen, Kilic, Ertugrul
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388917/
https://ncbi.nlm.nih.gov/pubmed/28395173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.006
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky