HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia

3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are widely used for secondary stroke prevention. Besides their lipid-lowering activity, pleiotropic effects on neuronal survival, angiogenesis, and neurogenesis have been described. In view of these observations, we were interested...

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Pubblicato in:Front Cell Neurosci
Autori principali: Kilic, Ertugrul, Reitmeir, Raluca, Kilic, Ülkan, Caglayan, Ahmet Burak, Beker, Mustafa Caglar, Kelestemur, Taha, Ethemoglu, Muhsine Sinem, Ozturk, Gurkan, Hermann, Dirk M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263103/
https://ncbi.nlm.nih.gov/pubmed/25565957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00422
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